diff --git a/src/scripts/clipperUI/regionSelector.tsx b/src/scripts/clipperUI/regionSelector.tsx
index 7a24fa54..fe82d154 100644
--- a/src/scripts/clipperUI/regionSelector.tsx
+++ b/src/scripts/clipperUI/regionSelector.tsx
@@ -25,6 +25,8 @@ interface RegionSelectorState {
 	keyboardSelectionInProgress?: boolean;
 	winWidth?: number;
 	winHeight?: number;
+	ariaLiveMessage?: string;
+	ariaAlertMessage?: string;
 }
 
 class RegionSelectorClass extends ComponentBase<RegionSelectorState, ClipperStateProp> {
@@ -105,6 +107,28 @@ class RegionSelectorClass extends ComponentBase<RegionSelectorState, ClipperStat
 		this.setState({ mousePosition: point});
 	}
 
+	/**
+	 * Get the direction message for screen reader based on key presses
+	 */
+	private getDirectionMessage(): string {
+		let directions: string[] = [];
+
+		if (this.keyDownDict[Constants.KeyCodes.up]) {
+			directions.push(Localization.getLocalizedString("WebClipper.Accessibility.ScreenReader.Up"));
+		}
+		if (this.keyDownDict[Constants.KeyCodes.down]) {
+			directions.push(Localization.getLocalizedString("WebClipper.Accessibility.ScreenReader.Down"));
+		}
+		if (this.keyDownDict[Constants.KeyCodes.left]) {
+			directions.push(Localization.getLocalizedString("WebClipper.Accessibility.ScreenReader.Left"));
+		}
+		if (this.keyDownDict[Constants.KeyCodes.right]) {
+			directions.push(Localization.getLocalizedString("WebClipper.Accessibility.ScreenReader.Right"));
+		}
+
+		return directions.join(" ");
+	}
+
 	/**
 	 * Define the ending point, and notify the main UI
 	 */
@@ -133,7 +157,9 @@ class RegionSelectorClass extends ComponentBase<RegionSelectorState, ClipperStat
 		if (e.which === Constants.KeyCodes.enter ) {
 			if (!this.state.selectionInProgress) {
 				this.startSelection({ x: this.state.mousePosition.x, y: this.state.mousePosition.y }, true /* fromKeyboard */);
+				this.setState({ ariaLiveMessage: Localization.getLocalizedString("WebClipper.Accessibility.ScreenReader.SelectionStarted") });
 			} else {
+				this.setState({ ariaAlertMessage: Localization.getLocalizedString("WebClipper.Accessibility.ScreenReader.SelectionComplete") });
 				this.stopSelection({ x: this.state.mousePosition.x, y: this.state.mousePosition.y });
 			}
 			e.preventDefault();
@@ -164,6 +190,13 @@ class RegionSelectorClass extends ComponentBase<RegionSelectorState, ClipperStat
 
 			this.setMousePosition(newPosition);
 
+			if (!e.repeat) {
+				let directionMessage = this.getDirectionMessage();
+				if (directionMessage) {
+					this.setState({ ariaLiveMessage: directionMessage });
+				}
+			}
+
 			if (this.state.selectionInProgress) {
 				this.moveSelection(newPosition);
 			}
@@ -431,6 +464,12 @@ class RegionSelectorClass extends ComponentBase<RegionSelectorState, ClipperStat
 				onmouseup={this.mouseUpHandler.bind(this)} ontouchstart={this.touchStartHandler.bind(this)}
 				ontouchmove={this.touchMoveHandler.bind(this)} ontouchend={this.touchEndHandler.bind(this)}
 				onkeydown={this.keyDownHandler.bind(this)} onkeyup={this.keyUpHandler.bind(this)}>
+				<div aria-live="polite" aria-atomic="true" className={Constants.Classes.srOnly}>
+					{this.state.ariaLiveMessage}
+				</div>
+				<div role="alert" aria-atomic="true" className={Constants.Classes.srOnly}>
+					{this.state.ariaAlertMessage}
+				</div>
 				<img id="cursor"  {...this.ref("cursor")} src={ExtensionUtils.getImageResourceUrl("crosshair_cursor.svg")}
 					width={Constants.Styles.customCursorSize + "px"} height={Constants.Styles.customCursorSize + "px"} />
 				<canvas id={Constants.Ids.outerFrame} {...this.ref(Constants.Ids.outerFrame)}></canvas>
diff --git a/src/strings.json b/src/strings.json
index 93969acb..bc3735a8 100644
--- a/src/strings.json
+++ b/src/strings.json
@@ -12,6 +12,12 @@
 	"WebClipper.Accessibility.ScreenReader.Footer": "User details",
 	"WebClipper.Accessibility.ScreenReader.Loading": "Loading...",
 	"WebClipper.Accessibility.ScreenReader.RegionSelectionCanvas": "Selection canvas",
+	"WebClipper.Accessibility.ScreenReader.SelectionStarted": "Selection started",
+	"WebClipper.Accessibility.ScreenReader.SelectionComplete": "Selection complete",
+	"WebClipper.Accessibility.ScreenReader.Up": "Up",
+	"WebClipper.Accessibility.ScreenReader.Down": "Down",
+	"WebClipper.Accessibility.ScreenReader.Left": "Left",
+	"WebClipper.Accessibility.ScreenReader.Right": "Right",
 	"WebClipper.Action.BackToHome": "Back",
 	"WebClipper.Action.Cancel": "Cancel",
 	"WebClipper.Action.Clip": "Clip",